In KOTCS, Indy mentions how he almost died of Typhus searching for El Dorado/Akator. Is there any source which says WHEN this first quest for Akator took place? 1920s? 1930s?
Nothing legit I don't think... Although I'm sure it's only a matter of time.
My guess is that it would have been pre TOD, probably when he was first out of University but post 1924 (although I'm sure someone will prove me wrong).