I would LOVE to see a new Indy adventure on the big screen, but I'm not holding my breath. Harrison appears to be free right now (according to IMDB), but Spielberg has a full slate, and George is busy being George....or whatever.
I watched Crystal Skull just the other night, and as flawed as it is (Mac, the monkeys, 3 times it drops) I still really like what George and Steven were doing. It's an Indy film set in the '50s, and also an homage to that period - the birth of rock n roll, "The Red Scare," atomic bombs, atomic age hysteria in film - including the UFO scare, giant ants from the movie
THEM! , etc., etc.
I love the period of the 1950's. It was a great time of change in The U.S., and all of that is reflected in Crystal Skull.
I can understand why some would not like the movie. It's quite a leap from the original Indy Trilogy, but I enjoy the film for what it is.
I would also love to see a new one! That time leading up to Crystal Skull was exciting, and I would love to do it again!